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Syllabus ( NANO 625 )


   Basic information
Course title: Nanobiomaterials
Course code: NANO 625
Lecturer: Assoc. Prof. Dr. İsrafil KÜÇÜK
ECTS credits: 7.5
GTU credits: 3 (3+0+0)
Year, Semester: 2020-2021, Spring
Level of course: Third Cycle (Doctoral)
Type of course: Compulsory
Language of instruction: English
Mode of delivery: Face to face
Pre- and co-requisites: None
Professional practice: No
Purpose of the course: This course aims to (1) provide a literature review on a use of nanomaterials as biomaterials in biotechnological applications, (2) to help students for better understanding fundamental and current characterization techniques which could be used or is the best method to examine Nanobiomaterials and (3) to demonstrate knowledge about enhanced Nanobiomaterials prepared using advanced engineering techniques in healthcare.
   Learning outcomes Up

Upon successful completion of this course, students will be able to:

  1. Students will be able to: Enhance comprehensively the knowledge about the structural, physical, chemical and biological properties of nanobiomaterials and the mechanisms occur between nanobiomaterials and the biological environments.

    Contribution to Program Outcomes

    1. To gain in-depth knowledge and experience about basic concepts and methods in nanoscience and nanotechnology.
    2. To be knowledgeable and practical about the production and characterization techniques of materials and devices in nano scale.
    3. To manage nanotechnology-focused solutions and products commercialization processes
    4. To be able to closely follow the industrial studies about nanoscience and nanotechnology in the world and in our country
    5. To take an active role in Product Development and Research-Development processes
    6. To follow the scientific publications in the field of nanotechnology and have an idea about the researches.
    7. Acquire scientific knowledge
    8. Design and conduct independent research projects
    9. Work effectively in multidisciplinary research teams
    10. Develop an awareness of continuous learning in relation with modern technology.
    11. Find out new ways to improve current knowledge
    12. To understand the basic principles and applications of new tools and / or software required for thesis work
    13. To be able to express ideas and findings related to the research topic both orally and in writing
    14. Write progress reports based on published documents, dissertations, articles
    15. Present and defence the research outcomes at seminars and conferences
    16. Demonstrating professional and ethical responsibility.
    17. Be aware of the importance of nanoscience and nanoengineering in understanding the working principles of the new generation nano devices

    Method of assessment

    1. Written exam
    2. Oral exam
    3. Homework assignment
    4. Seminar/presentation
  2. Upon successful completion of this course, students will be able to: It will enable the students to follow the literature on Nanobiomaterials.

    Contribution to Program Outcomes

    1. To gain in-depth knowledge and experience about basic concepts and methods in nanoscience and nanotechnology.
    2. To be knowledgeable and practical about the production and characterization techniques of materials and devices in nano scale.
    3. To manage nanotechnology-focused solutions and products commercialization processes
    4. To be able to closely follow the industrial studies about nanoscience and nanotechnology in the world and in our country
    5. To take an active role in Product Development and Research-Development processes
    6. To follow the scientific publications in the field of nanotechnology and have an idea about the researches.
    7. Acquire scientific knowledge
    8. Design and conduct independent research projects
    9. Work effectively in multidisciplinary research teams
    10. Develop an awareness of continuous learning in relation with modern technology.
    11. Find out new ways to improve current knowledge
    12. To understand the basic principles and applications of new tools and / or software required for thesis work
    13. To be able to express ideas and findings related to the research topic both orally and in writing
    14. Write progress reports based on published documents, dissertations, articles
    15. Present and defence the research outcomes at seminars and conferences
    16. Demonstrating professional and ethical responsibility.
    17. Be aware of the importance of nanoscience and nanoengineering in understanding the working principles of the new generation nano devices

    Method of assessment

    1. Written exam
    2. Oral exam
    3. Homework assignment
    4. Seminar/presentation
  3. Upon successful completion of this course, students will be able to: It will allow students to perform researches in Nanobiomaterials.

    Contribution to Program Outcomes

    1. To gain in-depth knowledge and experience about basic concepts and methods in nanoscience and nanotechnology.
    2. To be knowledgeable and practical about the production and characterization techniques of materials and devices in nano scale.
    3. To manage nanotechnology-focused solutions and products commercialization processes
    4. To be able to closely follow the industrial studies about nanoscience and nanotechnology in the world and in our country
    5. To take an active role in Product Development and Research-Development processes
    6. To follow the scientific publications in the field of nanotechnology and have an idea about the researches.
    7. Acquire scientific knowledge
    8. Design and conduct independent research projects
    9. Work effectively in multidisciplinary research teams
    10. Develop an awareness of continuous learning in relation with modern technology.
    11. Find out new ways to improve current knowledge
    12. To understand the basic principles and applications of new tools and / or software required for thesis work
    13. To be able to express ideas and findings related to the research topic both orally and in writing
    14. Write progress reports based on published documents, dissertations, articles
    15. Present and defence the research outcomes at seminars and conferences
    16. Demonstrating professional and ethical responsibility.
    17. Be aware of the importance of nanoscience and nanoengineering in understanding the working principles of the new generation nano devices

    Method of assessment

    1. Written exam
    2. Oral exam
    3. Homework assignment
    4. Seminar/presentation
   Contents Up
Week 1: Introduction to Nanobiomaterials and Nanotechnology: 1a. Historical background, 1b. Definitions and classification in Nanobiomaterials, 1c. Industrial significance and current issues in Nanobiomaterials
Week 2: Biocompatibility and its value
Week 3: Metallic Nanobiomaterials
Week 4: Nanobioceramic materials
Week 5: Nanobiopolymeric materials
Week 6: Nanobiohybrid materials
Week 7: Methods of Nanobiomaterial production
Week 8: Midterm Exam
Week 9: Characterization of Nanobiomaterials – XRD, Optical micr§oscopy and CLSM technique
Week 10: Characterization of Nanobiomaterials – Advanced electron microscopies (SEM, TEM, SPM, STEM, AFM, etc.)
Week 11: Characterization of Nanobiomaterials – Chemical analysis techniques (Infrared and Raman)
Week 12: Pop up Exam (Quiz)
Week 13: Utilization of Nanobiomaterials in Tissue Engineering – in particular, Natural, biodegradable and synthetic polymers
Week 14: Hydrogels and their use in tissue engineering
Week 15*: Student Presentations
Week 16*: Final Exam
Textbooks and materials: 1. Yi, Dong Kee, and Georgia C. Papaefthymiou, eds. Nanobiomaterials: Development and Applications. CRC Press, 2013.

2. Sitharaman, Balaji, ed. Nanobiomaterials handbook. CRC Press, 2011.
Recommended readings: .• https://nano.nature.com/

• Roger Narayan, Nanobiomaterials-Nanostructured Materials for Biomedical Applications, 2017.

• Vasıf Hasırcı, Nanobiomaterials: a review of the existing science and technology, and new approaches, J Biomater Sci Polym Ed. 2006;17(11):1241-68.
  * Between 15th and 16th weeks is there a free week for students to prepare for final exam.
Assessment Up
Method of assessment Week number Weight (%)
Mid-terms: 8 30
Other in-term studies: - 0
Project: 15 25
Homework: - 0
Quiz: 12 5
Final exam: 16 40
  Total weight:
(%)
   Workload Up
Activity Duration (Hours per week) Total number of weeks Total hours in term
Courses (Face-to-face teaching): 3 14
Own studies outside class: 5 14
Practice, Recitation: 0 0
Homework: 0 0
Term project: 2.5 2
Term project presentation: 3 1
Quiz: 1.5 1
Own study for mid-term exam: 8 4
Mid-term: 3 1
Personal studies for final exam: 7 4
Final exam: 3 1
    Total workload:
    Total ECTS credits:
*
  * ECTS credit is calculated by dividing total workload by 25.
(1 ECTS = 25 work hours)
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