• Basic information
• Learning outcomes
• Contents
• Assessment
• Workload

Learning outcomes

Upon successful completion of this course, students will be able to:

1. Appreciate types of chromosomes, compare and contrast mitosis and meiosis.

   Contribution to Program Outcomes

   1. To be able to define general concepts and problems related to Molecular Biology and Genetics and to produce solutions.
   2. To be able to define the structure-function relationship at the molecular level in cells and organisms.
   3. To be able to define life forms and their relationship with their environment.

   Method of assessment

   1. Written exam
2. Grasp Mendels laws, explain alele genes and their interactions, compare and contrast dominance and co-dominance and predict their modes of inheritance.

   Contribution to Program Outcomes

   1. To be able to define general concepts and problems related to Molecular Biology and Genetics and to produce solutions.
   2. To be able to define the structure-function relationship at the molecular level in cells and organisms.
   3. To be able to define life forms and their relationship with their environment.

   Method of assessment

   1. Written exam
3. Define sex-linked characteristics and describe their transmission.

   Contribution to Program Outcomes

   1. To be able to define general concepts and problems related to Molecular Biology and Genetics and to produce solutions.
   2. To be able to define life forms and their relationship with their environment.

   Method of assessment

   1. Written exam
4. Analyze a population using the Hardy-Weinberg equation, briefly describe population structures and isolation mechanisms and explain the genetical fundamentals of development and behaviors.

   Contribution to Program Outcomes

   1. To be able to explain the genetic information flow in organisms and populations.
   2. To be able to define life forms and their relationship with their environment.

   Method of assessment

   1. Written exam
5. Describes the molecular basis of development,developmental genes and stem cell therapies

   Contribution to Program Outcomes

   1. To be able to define general concepts and problems related to Molecular Biology and Genetics and to produce solutions.
   2. To be able to define the structure-function relationship at the molecular level in cells and organisms.
   3. To be able to define life forms and their relationship with their environment.
   4. To be able to follow current scientific and technological innovations with the awareness of continuous learning and to apply them in the field.

   Method of assessment

   1. Written exam
6. Differentiate the quantitative and qualitative genetics, describes the relations between environment and multigenes

   Contribution to Program Outcomes

   1. To be able to define general concepts and problems related to Molecular Biology and Genetics and to produce solutions.
   2. To be able to explain the genetic information flow in organisms and populations.
   3. To be able to define life forms and their relationship with their environment.

   Method of assessment

   1. Written exam
7. Describes human genetical diseases and their genetical basis

   Contribution to Program Outcomes

   1. To be able to define general concepts and problems related to Molecular Biology and Genetics and to produce solutions.
   2. To be able to define life forms and their relationship with their environment.

   Method of assessment

   1. Homework assignment
   2. Seminar/presentation
   3. Term paper
8. Differantiate the point, structural and numerical mutations

   Contribution to Program Outcomes

   1. To be able to define general concepts and problems related to Molecular Biology and Genetics and to produce solutions.
   2. To be able to define life forms and their relationship with their environment.

   Method of assessment

   1. Written exam
9. describes the genetic colsultation and analyse the human pedigrees

   Contribution to Program Outcomes

   1. To be able to define general concepts and problems related to Molecular Biology and Genetics and to produce solutions.
   2. To be able to define life forms and their relationship with their environment.

   Method of assessment

   1. Written exam
10. describes extranuclear inhertance, explains modern techniques in mitochondrial diseases

    Contribution to Program Outcomes

    1. To be able to define general concepts and problems related to Molecular Biology and Genetics and to produce solutions.
    2. To be able to define life forms and their relationship with their environment.
    3. To be able to follow current scientific and technological innovations with the awareness of continuous learning and to apply them in the field.

    Method of assessment

    1. Written exam
11. solves and analyse the problems and pedigree on Population Genetics, linked genes, sex linked genes, Quantitative Genetics and organelle inheritance

    Contribution to Program Outcomes

    1. To be able to define general concepts and problems related to Molecular Biology and Genetics and to produce solutions.
    2. To be able to define life forms and their relationship with their environment.

    Method of assessment

    1. Written exam

Contents
Week 1:	Key concepts and history of genetics: genotype, phenotype, homozygous, heterozygous, hemizygous.
Week 2:	Chromosomes, specialised chromosomes (lampbrush, polytene), mitosis, meiosis, production of gamets (spermatogenesis and oogenesis)
Week 3:	Mendelian genetics and its limitations, pedigree analysis
Week 4:	Genes: types of genes, structure of gene, relations between alleles and gene, gene expression, gene-environment interaction
Week 5:	Sex determination: male heterogamety, female heterogamety, haplodiploid sex determination, paternal genome elimination, hermaphrodite, effect of temperature in sex determination, sex linkage, phenotypic sex determination
Week 6:	Mutation: types of mutation, mutable genes, mutator genes, anti-mutator genes, transposones, genetic diseases
Week 7:	MID-TERM EXAM
Week 8:	Traits: qualitative traits, quantitative traits, quantitaive trait loci, polygenic effect
Week 9:	Extranuclear inheritance: mitochondrical genome, chloroplast genome
Week 10:	Linkage, crossing-over, gene mapping
Week 11:	Population genetics: organization of genetic variation
Week 12:	Population genetics: Darwinian selection
Week 13:	Population genetics: inbreeding, population subdivision, and migration
Week 14:	Behavioral genetics
Week 15*:	Preparation week for final exam
Week 16*:	FINAL EXAM
Textbooks and materials:	course material
Recommended readings:	Genetics: A Conceptual approach (Authors: Pierce, B.A.) Genetics: Analysis & Principles (Authors: Professor Brooker R.G.) Human Genetics: Concepts and Applications (Authors: Lewis, R.) Principles of Genetics, 7th Edition (Authors: D. Peter Snustad, Michael J. Simmons) Principles of Behavioral Genetics (Authors: Robert RH Anholt, Trudy F.C. Mackay)
	* Between 15th and 16th weeks is there a free week for students to prepare for final exam.

Assessment
Method of assessment	Week number	Weight (%)
Mid-terms:	8	30
Other in-term studies:		0
Project:		0
Homework:	15	20
Quiz:		0
Final exam:	16	50
	Total weight:	(%)

Workload
Activity	Duration (Hours per week)	Total number of weeks	Total hours in term
Courses (Face-to-face teaching):	3	15
Own studies outside class:	3	15
Practice, Recitation:	0	0
Homework:	7	1
Term project:	0	0
Term project presentation:	0	0
Quiz:	0	0
Own study for mid-term exam:	10	2
Mid-term:	2	1
Personal studies for final exam:	10	3
Final exam:	2	1
		Total workload:
		Total ECTS credits:	*
	* ECTS credit is calculated by dividing total workload by 25. (1 ECTS = 25 work hours)