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Syllabus ( MBG 272 )


   Basic information
Course title: Microbiology
Course code: MBG 272
Lecturer: Prof. Dr. Sedef TUNCA GEDİK
ECTS credits: 4
GTU credits: 3 (3-0-0)
Year, Semester: 2, Spring
Level of course: First Cycle (Undergraduate)
Type of course: Compulsory
Language of instruction: English
Mode of delivery: Face to face
Pre- and co-requisites: None
Professional practice: No
Purpose of the course: The objective of this course is to provide an overview of properties of microorganisms and impact of them on humans, principles of molecular microbiology, genetic engineering and biotechnology.
   Learning outcomes Up

Upon successful completion of this course, students will be able to:

  1. Gain knowledge about properties of microorganisms and impact of them on environment and humans.

    Contribution to Program Outcomes

    1. To be able to define general concepts and problems related to Molecular Biology and Genetics and to produce solutions.
    2. To be able to understand the relationship between matter and energy in organisms.
    3. To be able to define the structure-function relationship at the molecular level in cells and organisms.
    4. To be able to explain the genetic information flow in organisms and populations.

    Method of assessment

    1. Written exam
  2. Tell principles of microbial metabolism and molecular microbiology.

    Contribution to Program Outcomes

    1. To be able to define general concepts and problems related to Molecular Biology and Genetics and to produce solutions.
    2. To be able to understand the relationship between matter and energy in organisms.
    3. To be able to define the structure-function relationship at the molecular level in cells and organisms.

    Method of assessment

    1. Written exam
  3. Assess the importance of microorganisms in genetic engineering and biotechnology

    Contribution to Program Outcomes

    1. To be able to define general concepts and problems related to Molecular Biology and Genetics and to produce solutions.
    2. To be able to understand the relationship between matter and energy in organisms.
    3. To be able to define the structure-function relationship at the molecular level in cells and organisms.
    4. To be able to define life forms and their relationship with their environment.
    5. To be able to follow current scientific and technological innovations with the awareness of continuous learning and to apply them in the field.
    6. To be able to apply biological concepts to individual, social, economic, technologic and environmental issues and to develop sustainable approaches for problem solving.

    Method of assessment

    1. Written exam
   Contents Up
Week 1: Microorganisms and Microbiology
The Impact of Microorganisms on Humans
Week 2: Activities of Microbial Cells
Microorganisms and Their Environments
The importance of microscope in microbiology
Week 3: Cell Walls, Cell Surface Structures
Cell Inclusions, Microbial Locomotion
Week 4: Bacterial Cell Division
Measurement of bacterial growth
Factors affecting bacterial growth
Control of Microbial Growth
Week 5: Microbial Metabolism
Energy classes of microorganisms
Week 6: Structure of the Bacterial Genome
DNA replication
Week 7: MIDTERM EXAM

Transcription
Week 8: Translation
Introduction to regulation of gene expression
Week 9: Regulation of Gene Expresssion
*Negative control of transcription (repression, induction)
*Positive control of transcription
Week 10: Regulation of Gene Expresssion
*Global control
*Atenuation
*Alternative sigma factors
*Heat shock response
*Quorum sensing
Week 11: Genetic Engineering and Biotechnology
Strategies for gene cloning and expression
Week 12: Industrial microorganisms
Primary and secondary metabolites
Week 13: Molecular Basis of Mutation
Gene Transfer in Bacteria
Viruses and Viroloji
Week 14: Subviral agents: the viroids and the prions
Viral diseases
Diagnostic Microbiology
Week 15*: --------
Week 16*: FINAL EXAM
Textbooks and materials: Lecture notes
Recommended readings: [1] Madigan, M.T., Martinko, J.M., Bender, K.S., Buckley, D. H., Stahl, D.A. 15th Ed. Brock Biology of Microorganisims. Pearson Education Inc. San Francisco
[2] Madigan, M.T., Martinko, J.M., Bender, K.S., Buckley, D. H., Stahl, D.A. 11. Basım (Tercüme: Çökmüş, C.) Brock Mikroorganizmaların Biyolojisi. Palme Yayıncılık. Ankara
  * Between 15th and 16th weeks is there a free week for students to prepare for final exam.
Assessment Up
Method of assessment Week number Weight (%)
Mid-terms: 7 40
Other in-term studies: 0
Project: 0
Homework: 0
Quiz: 0
Final exam: 16 60
  Total weight:
(%)
   Workload Up
Activity Duration (Hours per week) Total number of weeks Total hours in term
Courses (Face-to-face teaching): 3 14
Own studies outside class: 2 14
Practice, Recitation: 0 0
Homework: 0 0
Term project: 0 0
Term project presentation: 0 0
Quiz: 0 0
Own study for mid-term exam: 2 7
Mid-term: 2 2
Personal studies for final exam: 2 5
Final exam: 2 1
    Total workload:
    Total ECTS credits:
*
  * ECTS credit is calculated by dividing total workload by 25.
(1 ECTS = 25 work hours)
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