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Syllabus ( MBG 305 )

   Basic information
Course title: Biochemistry I
Course code: MBG 305
Lecturer: Assoc. Prof. Dr. F. İnci ÖZDEMİR
ECTS credits: 5
GTU credits: 3 (3+0+0)
Year, Semester: 3, Fall
Level of course: First Cycle (Undergraduate)
Type of course: Compulsory
Language of instruction: English
Mode of delivery: Face to face
Pre- and co-requisites: CHEM 103 & CHEM 106
Professional practice: No
Purpose of the course: Teaching the life processes at the molecular and cellular level; the relationship between protein structure and function; the enzymes kinetic and structural properties; the central energy metabolism as well as the basic chemical properties that underlie these processes.
became familiar with the chemical composition and bheviour of the biological macromolecules.
understand the biochemical basis of cellular signal transduction.
   Learning outcomes Up

Upon successful completion of this course, students will be able to:

  1. Explain the concept of cell. Recognize the chemical properties of biological molecules and describe their functions in the organism.

    Contribution to Program Outcomes

    1. To be able to define general concepts and problems related to Molecular Biology and Genetics and to produce solutions.
    2. To be able to define the structure-function relationship at the molecular level in cells and organisms.
    3. To be able to explain the genetic information flow in organisms and populations.
    4. To be able to drive hypotheses using existing knowledge, designing and conducting experiment for problem solving and make correct interpretation of the results obtained from the experiment.

    Method of assessment

    1. Written exam
    2. Homework assignment
  2. Define the structure of proteins and classify proteins according to their structure.

    Contribution to Program Outcomes

    1. To be able to define general concepts and problems related to Molecular Biology and Genetics and to produce solutions.
    2. To be able to define the structure-function relationship at the molecular level in cells and organisms.

    Method of assessment

    1. Written exam
    2. Homework assignment
  3. Identify the levels of structure in proteins and describe the physical and chemical components for the stabilization of these structures.

    Contribution to Program Outcomes

    1. To be able to define the structure-function relationship at the molecular level in cells and organisms.
    2. To be able to drive hypotheses using existing knowledge, designing and conducting experiment for problem solving and make correct interpretation of the results obtained from the experiment.

    Method of assessment

    1. Written exam
    2. Homework assignment
  4. Interpret plots of enzyme kinetic data and describe representative mechanisms of enzyme catalysis

    Contribution to Program Outcomes

    1. To be able to define the structure-function relationship at the molecular level in cells and organisms.
    2. To be able to explain the genetic information flow in organisms and populations.
    3. To be able to drive hypotheses using existing knowledge, designing and conducting experiment for problem solving and make correct interpretation of the results obtained from the experiment.

    Method of assessment

    1. Written exam
    2. Homework assignment
  5. Explain the basic concepts of nucleotides and nucleic acids and describe the components and functions of nucleotides

    Contribution to Program Outcomes

    1. To be able to define general concepts and problems related to Molecular Biology and Genetics and to produce solutions.
    2. To be able to understand the relationship between matter and energy in organisms.
    3. To be able to define the structure-function relationship at the molecular level in cells and organisms.
    4. To be able to follow current scientific and technological innovations with the awareness of continuous learning and to apply them in the field.

    Method of assessment

    1. Written exam
    2. Homework assignment
  6. Explain Structure of carbohydrates lipids. Classify carbohydrates and lipids and defines their structural properties.

    Contribution to Program Outcomes

    1. To be able to define general concepts and problems related to Molecular Biology and Genetics and to produce solutions.
    2. To be able to define the structure-function relationship at the molecular level in cells and organisms.

    Method of assessment

    1. Written exam
    2. Homework assignment
   Contents Up
Week 1: The Foundations of Biochemistry
Week 2: Physical Properties of Water
Week 3: Amino Acids, Peptides, and Proteins
Week 4: Protein Structure and Function
Week 5: Enzymes
Week 6: Mid-term Exam
Week 7: Enzyme Kinetics
Week 8: Nucleotides and Biochemistry of Nucleic Acids
Week 9: DNA and RNA
Week 10: Carbonhydrates
Week 11: Basic Reactions of Carbohydrates
Week 12: Lipids
Week 13: Biological Membranes and Transport
Week 14: Biochemistry of Signal Transduction
Week 15*: General Evaluation
Week 16*: Final Exam
Textbooks and materials:
Recommended readings: Lehninger Prenciples of Biochemistry (5. Baskı) David L Nelson ve Michael M. Cox; Stryer Biochemistry (6. Baskı) Jermy M. Berg (2009)
  * Between 15th and 16th weeks is there a free week for students to prepare for final exam.
Assessment Up
Method of assessment Week number Weight (%)
Mid-terms: 5,9 50
Other in-term studies: 0
Project: 0
Homework: 10 10
Quiz: 0
Final exam: 16 40
  Total weight:
(%)
   Workload Up
Activity Duration (Hours per week) Total number of weeks Total hours in term
Courses (Face-to-face teaching): 3 13
Own studies outside class: 2 13
Practice, Recitation: 0 0
Homework: 0 1
Term project: 0 0
Term project presentation: 0 0
Quiz: 0 0
Own study for mid-term exam: 14 2
Mid-term: 3 1
Personal studies for final exam: 14 2
Final exam: 3 1
    Total workload:
    Total ECTS credits:
*
  * ECTS credit is calculated by dividing total workload by 25.
(1 ECTS = 25 work hours)
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