Syllabus ( MBG 422 )
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Basic information
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| Course title: |
Molecular Evolution |
| Course code: |
MBG 422 |
| Lecturer: |
Assoc. Prof. Dr. Hülya Akdemir
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| ECTS credits: |
5 |
| GTU credits: |
3 (3+0+0) |
| Year, Semester: |
4, Fall |
| Level of course: |
First Cycle (Undergraduate) |
| Type of course: |
Elective
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| Language of instruction: |
English
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| Mode of delivery: |
Face to face
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| Pre- and co-requisites: |
none |
| Professional practice: |
No |
| Purpose of the course: |
The objective of this course is to provide an overview of how genes and genomes evolve over time. This will be achieved by highlighting the general concept of evolution and evolutionary thinking. |
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Learning outcomes
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Upon successful completion of this course, students will be able to:
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Explain the history and the basic laws of molecular evolution
Contribution to Program Outcomes
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To be able to define general concepts and problems related to Molecular Biology and Genetics and to produce solutions.
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To be able to define the structure-function relationship at the molecular level in cells and organisms.
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To be able to comprehend the history and nature of scientific thinking and to apply them to problems in the field.
Method of assessment
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Written exam
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Oral exam
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Tell the molecular basis of evolution
Contribution to Program Outcomes
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To be able to define general concepts and problems related to Molecular Biology and Genetics and to produce solutions.
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To be able to define the structure-function relationship at the molecular level in cells and organisms.
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To be able to explain the genetic information flow in organisms and populations.
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To be able to define life forms and their relationship with their environment.
Method of assessment
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Oral exam
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Use knowledge of gene families and genome architecture
Contribution to Program Outcomes
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To be able to define general concepts and problems related to Molecular Biology and Genetics and to produce solutions.
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To be able to explain the genetic information flow in organisms and populations.
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To be able to define life forms and their relationship with their environment.
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To be able to comprehend the history and nature of scientific thinking and to apply them to problems in the field.
Method of assessment
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Homework assignment
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Contents
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| Week 1: |
Introduction |
| Week 2: |
Life and Evolution
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| Week 3: |
History of Evolutionary Tought
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| Week 4: |
Molecular basis of evolution -Basic concepts of molecular evolution
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| Week 5: |
The Pattern of Evolution -Evolution by Natural Selection
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| Week 6: |
The mechanism of evolutionary changes
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| Week 7: |
The mechanism of evolutionary changes (continue)
Mid-term exam
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| Week 8: |
Genetic Drift and Molecular Evolution |
| Week 9: |
The Neutral Theory of Molecular Evolution
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| Week 10: |
Molecular clocks |
| Week 11: |
Phylogenetic trees |
| Week 12: |
Where New Genes Come From? -Evolution of gene families |
| Week 13: |
How biological molecules evolve?
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| Week 14: |
Presentations |
| Week 15*: |
General overview |
| Week 16*: |
Final exam |
| Textbooks and materials: |
Scott Orland Rogers - Integrated molecular evolution-CRC Press (2017)
Jon Herron, Scott Freeman - Evolutionary analysis-Pearson (2015)
Norman A. Johnson* Darwinian Detectives: Revealing the Natural History of Genes and Genomes-Oxford University Press (2007)
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| Recommended readings: |
Scott Orland Rogers - Integrated molecular evolution-CRC Press (2017)
Jon Herron, Scott Freeman - Evolutionary analysis-Pearson (2015)
Norman A. Johnson* Darwinian Detectives: Revealing the Natural History of Genes and Genomes-Oxford University Press (2007)
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* Between 15th and 16th weeks is there a free week for students to prepare for final exam.
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Assessment
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| Method of assessment |
Week number |
Weight (%) |
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| Mid-terms: |
7 |
35 |
| Other in-term studies: |
0 |
0 |
| Project: |
9-16 |
15 |
| Homework: |
0 |
0 |
| Quiz: |
0 |
0 |
| Final exam: |
16 |
50 |
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Total weight: |
(%) |
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Workload
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| Activity |
Duration (Hours per week) |
Total number of weeks |
Total hours in term |
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| Courses (Face-to-face teaching): |
3 |
14 |
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| Own studies outside class: |
0 |
0 |
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| Practice, Recitation: |
0 |
0 |
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| Homework: |
3 |
5 |
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| Term project: |
0 |
0 |
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| Term project presentation: |
0 |
0 |
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| Quiz: |
0 |
0 |
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| Own study for mid-term exam: |
5 |
7 |
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| Mid-term: |
2 |
1 |
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| Personal studies for final exam: |
5 |
5 |
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| Final exam: |
3 |
1 |
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Total workload: |
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Total ECTS credits: |
* |
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* ECTS credit is calculated by dividing total workload by 25.
(1 ECTS = 25 work hours)
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