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Syllabus ( MBG 434 )

   Basic information
Course title: Biology Of Cancer
Course code: MBG 434
Lecturer: Prof. Dr. Asuman DEMİROĞLU-ZERGEROĞLU
ECTS credits: 5
GTU credits: 3 (3+0+0)
Year, Semester: 4, Fall
Level of course: First Cycle (Undergraduate)
Type of course: Area Elective
Language of instruction: English
Mode of delivery: Face to face
Pre- and co-requisites: None
Professional practice: No
Purpose of the course: Understanding of the mechanism of carcinogenesis at molecular level and related genes involved in the process
   Learning outcomes Up

Upon successful completion of this course, students will be able to:

  1. Identify the ability to characterise cancer at molecular and cellular level

    Contribution to Program Outcomes

    1. To be able to define general concepts and problems related to Molecular Biology and Genetics and to produce solutions.
    2. To be able to define the structure-function relationship at the molecular level in cells and organisms.

    Method of assessment

    1. Written exam
    2. Seminar/presentation
    3. Term paper
  2. Identify the key genes during carcinogenesis

    Contribution to Program Outcomes

    1. To be able to define general concepts and problems related to Molecular Biology and Genetics and to produce solutions.
    2. To be able to define the structure-function relationship at the molecular level in cells and organisms.

    Method of assessment

    1. Written exam
    2. Seminar/presentation
    3. Term paper
  3. Explain the biological principles underlying the causes and treatments

    Contribution to Program Outcomes

    1. To be able to define general concepts and problems related to Molecular Biology and Genetics and to produce solutions.
    2. To be able to define the structure-function relationship at the molecular level in cells and organisms.

    Method of assessment

    1. Written exam
    2. Seminar/presentation
    3. Term paper
  4. Understanding the ethical rules and taking responsibility

    Contribution to Program Outcomes

    1. To be able to embrace academic ethical rules and to be able to act with a sense of responsibility.

    Method of assessment

    1. Written exam
    2. Seminar/presentation
    3. Term paper
   Contents Up
Week 1: The Nature of Cancer
Week 2: Tumor Viruses
Week 3: Cellular Oncogenes
Week 4: Growth Factors and Their Receptors
Week 5: Cytoplasmic Signalling Circuitry Programs
Week 6: Tumor Suppressor Genes
Week 7: Control of Cell Cycle Clock
Week 8: Apoptosis: Master Guradian and Executioner
Week 9: Genetic instability, Chromosomes and repair
Week 10: Presentations and Discussions
Week 11: Presentations and Discussions
Week 12: Presentations and Discussions
Week 13: Presentations and Discussions
Week 14: Presentations and Discussions
Week 15*: General Discussion
Week 16*: Final Exam
Textbooks and materials: The Biology of Cancer by Robert A. Weinberg. Garland Science 2014
Second addition
Recommended readings: 1-RJB King: Cancer Biology, Pearson Education Limited, (Second addition), Essex, 2000.
2-The Biology of Cancer by Robert A. Weinberg. Garland Science 2014
  * Between 15th and 16th weeks is there a free week for students to prepare for final exam.
Assessment Up
Method of assessment Week number Weight (%)
Mid-terms: 0
Other in-term studies: 0
Project: 10,11,12,13,14 40
Homework: 0
Quiz: 0
Final exam: 16 60
  Total weight:
(%)
   Workload Up
Activity Duration (Hours per week) Total number of weeks Total hours in term
Courses (Face-to-face teaching): 3 14
Own studies outside class: 3 14
Practice, Recitation: 0 0
Homework: 0 0
Term project: 1 5
Term project presentation: 1 5
Quiz: 0 0
Own study for mid-term exam: 0 0
Mid-term: 0 0
Personal studies for final exam: 2 14
Final exam: 1 1
    Total workload:
    Total ECTS credits:
*
  * ECTS credit is calculated by dividing total workload by 25.
(1 ECTS = 25 work hours)
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