Syllabus ( BENG 456 )
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Basic information
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| Course title: |
Applications of Cancer Biology in Bioengineering |
| Course code: |
BENG 456 |
| Lecturer: |
Prof. Dr. Elif Damla ARISAN
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| ECTS credits: |
5 |
| GTU credits: |
3 () |
| Year, Semester: |
4, Spring |
| Level of course: |
First Cycle (Undergraduate) |
| Type of course: |
Departmental Elective
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| Language of instruction: |
English
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| Mode of delivery: |
Face to face
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| Pre- and co-requisites: |
none |
| Professional practice: |
No |
| Purpose of the course: |
Within the scope of the course, it is an introduction to cancer biology and includes the transformation of a cell into a cancerous cell, different types of cancer, associated therapy models, and innovative diagnostic methods. |
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Learning outcomes
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Upon successful completion of this course, students will be able to:
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List current techniques used in Cancer Molecular Biology
Contribution to Program Outcomes
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Acquire knowledge for research methods which are required to develop novel application methods
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Convert biological, chemical, physical and mathematical principles into novel applications for the benefit of society,
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Conduct and develop bioengineering applications for relevant sectors such as health and agricultural industry.
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Develop an awareness of continuous learning in relation with modern technology.
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Demonstrate sufficiency in English to follow literature, present technical projects and write articles
Method of assessment
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Written exam
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Define metastatic cancer progression, formation and development stages of cancer
Contribution to Program Outcomes
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Acquire knowledge for research methods which are required to develop novel application methods
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Combine, Interpret, and analyze different subfields of bioengineering
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Demonstrate sufficiency in English to follow literature, present technical projects and write articles
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Understand the social and global importance of proposed solutions
Method of assessment
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Written exam
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Term paper
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Define current therapeutic targets related to the molecular biology of cancer.
Contribution to Program Outcomes
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Acquire knowledge for research methods which are required to develop novel application methods
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Design processes for the investigation of bioengineering problems, collect data, analyze and interpret the results.
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Combine, Interpret, and analyze different subfields of bioengineering
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Combine and effectively integrate knowledge acquired from different disciplines.
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Find out new methods to improve his/her knowledge.
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Demonstrate sufficiency in English to follow literature, present technical projects and write articles
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Understand the social and global importance of proposed solutions
Method of assessment
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Written exam
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Contents
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| Week 1: |
Introduction to cancer and general definitions |
| Week 2: |
Epidemiology: Global cancer burden |
| Week 3: |
From normal cell to malignant cell: Cellular factors |
| Week 4: |
Molecular mechanisms involved in transition from normal cell to malignant cell |
| Week 5: |
Introduction to environmental factors leading to transition from normal cell to malignant cell |
| Week 6: |
Environmental factors leading to transition from normal cell to malignant cell |
| Week 7: |
Introduction to metastasis
Mid-term exam |
| Week 8: |
Metastasis mechanisms |
| Week 9: |
Conventional therapeutics |
| Week 10: |
Personalized cancer treatment |
| Week 11: |
Novel diagnostic methods |
| Week 12: |
Big data for cancer research |
| Week 13: |
Bioengineering for cancer diagnosis and treatment & project presentations |
| Week 14: |
New developments in cancer biology |
| Week 15*: |
- |
| Week 16*: |
Final exam |
| Textbooks and materials: |
"Molecular Biology and Cancer: Mechanisms, Targets and Therapeutics" (2nd edition) - Lauren Pecorino, Oxford University Press
The Molecular Biology of Cancer- Micheal Khan, Stella Plengaris, Wiley-Blackwell |
| Recommended readings: |
“Hallmarks of cancer: the next generation.” Hanahan, Douglas, and Robert A Weinberg. Cell vol. 144,5 , 2011: 646-74. doi:10.1016/j.cell.2011.02.013
"Cancer Biology and Treatment (Oxford Biology Primers)" Divan, Royds, 2020, Oxford University Press
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* Between 15th and 16th weeks is there a free week for students to prepare for final exam.
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Assessment
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| Method of assessment |
Week number |
Weight (%) |
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| Mid-terms: |
7 |
30 |
| Other in-term studies: |
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0 |
| Project: |
13 |
30 |
| Homework: |
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0 |
| Quiz: |
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0 |
| Final exam: |
1 |
40 |
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Total weight: |
(%) |
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Workload
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| Activity |
Duration (Hours per week) |
Total number of weeks |
Total hours in term |
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| Courses (Face-to-face teaching): |
3 |
14 |
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| Own studies outside class: |
2 |
14 |
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| Practice, Recitation: |
0 |
0 |
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| Homework: |
0 |
0 |
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| Term project: |
2 |
13 |
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| Term project presentation: |
1 |
1 |
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| Quiz: |
0 |
0 |
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| Own study for mid-term exam: |
2 |
7 |
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| Mid-term: |
2 |
1 |
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| Personal studies for final exam: |
2 |
5 |
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| Final exam: |
2 |
1 |
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Total workload: |
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Total ECTS credits: |
* |
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* ECTS credit is calculated by dividing total workload by 25.
(1 ECTS = 25 work hours)
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