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Contents
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Week 1: |
Introduction to Systems Neurobiology, Basics of Cellular Neurobiology |
Week 2: |
Functional and spatial organization of brain as a system |
Week 3: |
Basics of Neurochemistry, Brain Metabolism, Neurodevelopment Project I |
Week 4: |
Cell types in brain (neuron, glia), intercellular and intracellular interactions in nervous system Quiz |
Week 5: |
Glial Cells in Brain, Functions and Interactions |
Week 6: |
Brain Connectomics, Interconnection of neurons, information transfer in brain |
Week 7: |
Networks in Brain for cognitive functions and behavioral tasks (vision, memory, perception) Quiz |
Week 8: |
Neuro-omics: Transcriptome, Proteome, Metabolome and Interactome approaches for nervous system
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Week 9: |
Case Study I-Brain Tumors: Molecular mechanisms, systems biology approaches |
Week 10: |
Case Study I-Brain Tumors: Statistical inference of interactions via genome-scale datasets Quiz |
Week 11: |
Case Study II-Neural Stem Cells: Molecular mechanisms of stem cells, systems biology approaches Project II |
Week 12: |
Case Study II-Neural Stem Cells: Modeling of metabolic interactions Homework I |
Week 13: |
Case Study III-Neurodegenerative Diseases: Molecular mechanisms, systems biology approaches Quiz
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Week 14: |
Case Study III-Neurodegenerative Diseases: Modeling of protein-protein interactions
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Week 15*: |
General Overview
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Week 16*: |
Project III
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Textbooks and materials: |
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Recommended readings: |
1) N. Le Novere (Eds.), "Computational Systems Neurobiology", Springer, 2012
2) S. Brady, G. Siegel, R.W. Albers, D. Price, "Basic Neurochemistry: Principles of Molecular, Cellular and Medical Neurobiology", Academic Press, 8th Edition, 2011 |
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* Between 15th and 16th weeks is there a free week for students to prepare for final exam.
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