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Syllabus ( BENG 223 )

   Basic information
Course title: Molecular Biology of the Cell
Course code: BENG 223
Lecturer: Assoc. Prof. Dr. Bengü ERGÜDEN
ECTS credits: 4
GTU credits: 3 ()
Year, Semester: 2, Spring
Level of course: First Cycle (Undergraduate)
Type of course: Compulsory
Language of instruction: English
Mode of delivery: Face to face
Pre- and co-requisites: none
Professional practice: No
Purpose of the course: To introduce chemical and physical structure of the prokaryotic and eukaryotic cells as well as cellular events in these systems at molecular level.
   Learning outcomes Up

Upon successful completion of this course, students will be able to:

  1. describe the structure and structure-function relationship of eukaryotic cells at the molecular level

    Contribution to Program Outcomes

    1. Acquire knowledge on biological, chemical, physical and mathematical principles which constitute the basis of bioengineering applications
    2. Convert biological, chemical, physical and mathematical principles into novel applications for the benefit of society,
    3. Work effectively in multi-disciplinary research teams

    Method of assessment

    1. Written exam
  2. describe the functional mechanisms of cellular structures using their knowledge about basic genetic and biochemical events

    Contribution to Program Outcomes

    1. Acquire knowledge on biological, chemical, physical and mathematical principles which constitute the basis of bioengineering applications

    Method of assessment

    1. Written exam
  3. define how cellular signal transduction mechanisms activate and suppress various cellular pathways

    Contribution to Program Outcomes

    1. Acquire knowledge on biological, chemical, physical and mathematical principles which constitute the basis of bioengineering applications

    Method of assessment

    1. Written exam
   Contents Up
Week 1: Cells, Genome, Cell Chemistry and Biosynthesis
Week 2: Proteins, DNA and RNA Structure
Week 3: Chromosomes and Genomes
Week 4: DNA Replication, Repair, and Recombination
Quiz I
Week 5: How Cells Read the Genome: Transcription
Week 6: How Cells Read the Genome: Translation
Quiz II
Week 7: Control of Gene Expression
Week 8: Manipulating Proteins, DNA and RNA
Midterm Exam
Week 9: Membrane Structure, Membrane Transport of Small Molecules
Week 10: Intracellular Compartments and Protein Sorting
Quiz III
Week 11: Intracellular Vesicular Traffic
Week 12: Energy Conversion: Mitochondria and Chloroplasts
Quiz IV
Week 13: The Cytoskeleton
Week 14: The Cell Cycle
Week 15*: -
Week 16*: Final Exam
Textbooks and materials: Molecular Biology of the Cell. Bruce Alberts, Dennis Bray, James Watson, and Julian Lewis. 6th Edition, 2015. Garland Science.
Recommended readings: 1) Karp's Cell and Molecular Biology: Concepts and Experiments, Gerald Karp, Janet Iwasa, Wallace Marshall, 8th Edition. Wiley.
2) Molecular Cell Biology. Harvey Lodish, Arnold Berk, Chris A. Kaiser, Monty Krieger, Matthew P. Scott, Anthony Bretscher, Hidde Ploegh, Paul Matsudaira. 8th Edition. Macmillan Learning.
  * Between 15th and 16th weeks is there a free week for students to prepare for final exam.
Assessment Up
Method of assessment Week number Weight (%)
Mid-terms: 8 30
Other in-term studies: 0
Project: 0
Homework: 0
Quiz: 4, 6,10, 12 20
Final exam: 16 50
  Total weight:
(%)
   Workload Up
Activity Duration (Hours per week) Total number of weeks Total hours in term
Courses (Face-to-face teaching): 3 13
Own studies outside class: 3 14
Practice, Recitation: 0 0
Homework: 1 0
Term project: 0 0
Term project presentation: 0 0
Quiz: 1 4
Own study for mid-term exam: 5 1
Mid-term: 2 1
Personal studies for final exam: 10 1
Final exam: 2 1
    Total workload:
    Total ECTS credits:
*
  * ECTS credit is calculated by dividing total workload by 25.
(1 ECTS = 25 work hours)
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