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Syllabus ( BENG 361 )


   Basic information
Course title: Enzyme Engineering
Course code: BENG 361
Lecturer: Prof. Dr. Barış BİNAY
ECTS credits: 5
GTU credits: 3 ()
Year, Semester: 3, Fall
Level of course: First Cycle (Undergraduate)
Type of course: Compulsory
Language of instruction: English
Mode of delivery: Face to face
Pre- and co-requisites: none
Professional practice: No
Purpose of the course: This course is aimed to provide the necessary background for providing students with knowledge and skills about enzymes and their production. In the lecture, information about enzyme kinetics and its working mechanisms, enzyme stabilization, purification and enzyme reactors is given to students in order to provide skills for enzyme engineering and its applications in the industry, and the lecture provides ability to solve problems related to enzymatic reactions.
   Learning outcomes Up

Upon successful completion of this course, students will be able to:

  1. Define enzymes and their types.

    Contribution to Program Outcomes

    1. Acquire knowledge on biological, chemical, physical and mathematical principles which constitute the basis of bioengineering applications

    Method of assessment

    1. Homework assignment
    2. Seminar/presentation
  2. Identify enzyme kinetic and its mechanism.

    Contribution to Program Outcomes

    1. Convert biological, chemical, physical and mathematical principles into novel applications for the benefit of society,

    Method of assessment

    1. Written exam
  3. Solve the problems to enzymatic reaction kinetics.

    Contribution to Program Outcomes

    1. Acquire knowledge on current bioengineering applications from the industrial and scientific aspects

    Method of assessment

    1. Written exam
   Contents Up
Week 1: Introduction to Enzyme Engineering
Week 2: Enzyme Biology and its Chemistry, Classification of Enzymes
Homework
Week 3: Enzyme Mechanism and Enzyme Kinetics
Week 4: Enzyme Synthesis and its Activity Regulation
Homework
Week 5: Qiagene histag purification
Quiz
Week 6: Enzyme Engineering Techniques
Week 7: Enzyme Engineering Industrial Applications
Week 8: Enzyme Engineering Industrial Applications
Midterm I
Week 9: Recombinant DNA Technology for Enzyme Engineering
Week 10: Bioinfomatics for Enzyme
Week 11: Modelling for Enzyme Engineering

Week 12: Modelling Techniques
Week 13: Molecular Docking
Week 14: Presentations
Week 15*: .
Week 16*: Final
Textbooks and materials:
Recommended readings: Enzyme Engineering - Methods and Protocols | James C. Samuelson
Fundamentals of Enzyme Engineering
  * Between 15th and 16th weeks is there a free week for students to prepare for final exam.
Assessment Up
Method of assessment Week number Weight (%)
Mid-terms: 8 30
Other in-term studies: 14 20
Project: 0 0
Homework: 1, 3 5
Quiz: 5 5
Final exam: 16 40
  Total weight:
(%)
   Workload Up
Activity Duration (Hours per week) Total number of weeks Total hours in term
Courses (Face-to-face teaching): 3 14
Own studies outside class: 3 14
Practice, Recitation: 0 0
Homework: 3 2
Term project: 0 0
Term project presentation: 0 0
Quiz: 0 0
Own study for mid-term exam: 4 4
Mid-term: 2 1
Personal studies for final exam: 4 4
Final exam: 2 1
    Total workload:
    Total ECTS credits:
*
  * ECTS credit is calculated by dividing total workload by 25.
(1 ECTS = 25 work hours)
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