• Basic information
• Learning outcomes
• Contents
• Assessment
• Workload

Learning outcomes

Upon successful completion of this course, students will be able to:

1. Grasp the fundamentals of bioprocessing steps and bioreactor types

   Contribution to Program Outcomes

   1. Understand design and production processes in bioengineering applications.
   2. Apply mathematical analysis and modeling methods for bioengineering design and production processes.

   Method of assessment

   1. Written exam
   2. Term paper
2. Gain competence in the computational evaluation of bioprocesses

   Contribution to Program Outcomes

   1. Apply mathematical analysis and modeling methods for bioengineering design and production processes.
   2. Design processes for the investigation of bioengineering problems, collect data, analyze and interpret the results.

   Method of assessment

   1. Written exam
   2. Term paper
3. Design appropriate production conditions to be used in bioprocess applications at a basic level

   Contribution to Program Outcomes

   1. Apply mathematical analysis and modeling methods for bioengineering design and production processes.
   2. Design processes for the investigation of bioengineering problems, collect data, analyze and interpret the results.

   Method of assessment

   1. Written exam
   2. Term paper

Contents
Week 1:	Introduction of course. Assignment of the projects. Structure of biotechnological processes, structure of bioreactors, operating modes of bioprocesses, classification of bioprocesses based on oxygen demands. Project assignment-I
Week 2:	Process design development, Material balances
Week 3:	Material Balances, Stoichiometry Project assignment-II
Week 4:	Stoichiometry, Design of growth media Problem solution-I Project assignment-III
Week 5:	Mixing Project assignment-IV
Week 6:	Mass Transfer Problem solution-II
Week 7:	Project study-I
Week 8:	Energy balance Problem solution-III Project assignment-V
Week 9:	Heat transfer
Week 10:	Sterilization, Project study-II
Week 11:	Integration of transport processes and bioreactions, Types of bioreactors Problem solution-IV Project assignment-VI
Week 12:	Equipment design, Project study-III Project assignment-VII
Week 13:	Bioseparations – unit operations
Week 14:	Project study-IV
Week 15*:	Project Presentations
Week 16*:	Final Exam
Textbooks and materials:	Mustafa Türker (2005) Biyoreaksiyon Mühendisliği, Su Vakfı Yayınları Pauline M. Doran (2013) Bioprocess Engineering Principles ML Shuler and F Kargı (2002) Bioprocess Engineering Principles, Prentice Hall
Recommended readings:	Fiechter, A. (1993). Bioprocess design and control. Springer-Verlag.
	* Between 15th and 16th weeks is there a free week for students to prepare for final exam.

Assessment
Method of assessment	Week number	Weight (%)
Mid-terms:		0
Other in-term studies:		0
Project:	1,3,4,5,8,11,12,15	60
Homework:		0
Quiz:		0
Final exam:	16	40
	Total weight:	(%)

Workload
Activity	Duration (Hours per week)	Total number of weeks	Total hours in term
Courses (Face-to-face teaching):	3	14
Own studies outside class:	7	14
Practice, Recitation:	2	4
Homework:	0	0
Term project:	3	4
Term project presentation:	4	1
Quiz:	0	0
Own study for mid-term exam:	0	0
Mid-term:	0	0
Personal studies for final exam:	6	6
Final exam:	4	1
		Total workload:
		Total ECTS credits:	*
	* ECTS credit is calculated by dividing total workload by 25. (1 ECTS = 25 work hours)