ECTS @ IUE ECTS @ IUE ECTS @ IUE ECTS @ IUE ECTS @ IUE ECTS @ IUE ECTS @ IUE

Syllabus ( BENG 456 )


   Basic information
Course title: Applications of Cancer Biology in Bioengineering
Course code: BENG 456
Lecturer: Assist. Prof. Onur SERÇİNOĞLU
ECTS credits: 5
GTU credits: 3 ()
Year, Semester: 4, Spring
Level of course: First Cycle (Undergraduate)
Type of course: Departmental Elective
Language of instruction: English
Mode of delivery: Face to face
Pre- and co-requisites: none
Professional practice: No
Purpose of the course: Within the scope of the course, it is an introduction to cancer biology and includes the transformation of a cell into a cancerous cell, different types of cancer, associated therapy models, and innovative diagnostic methods.
   Learning outcomes Up

Upon successful completion of this course, students will be able to:

  1. List current techniques used in Cancer Molecular Biology

    Contribution to Program Outcomes

    1. Acquire knowledge for research methods which are required to develop novel application methods
    2. Convert biological, chemical, physical and mathematical principles into novel applications for the benefit of society,
    3. Conduct and develop bioengineering applications for relevant sectors such as health and agricultural industry.
    4. Develop an awareness of continuous learning in relation with modern technology.
    5. Demonstrate sufficiency in English to follow literature, present technical projects and write articles

    Method of assessment

    1. Written exam
  2. Define metastatic cancer progression, formation and development stages of cancer

    Contribution to Program Outcomes

    1. Acquire knowledge for research methods which are required to develop novel application methods
    2. Combine, Interpret, and analyze different subfields of bioengineering
    3. Demonstrate sufficiency in English to follow literature, present technical projects and write articles
    4. Understand the social and global importance of proposed solutions

    Method of assessment

    1. Written exam
    2. Term paper
  3. Define current therapeutic targets related to the molecular biology of cancer.

    Contribution to Program Outcomes

    1. Acquire knowledge for research methods which are required to develop novel application methods
    2. Design processes for the investigation of bioengineering problems, collect data, analyze and interpret the results.
    3. Combine, Interpret, and analyze different subfields of bioengineering
    4. Combine and effectively integrate knowledge acquired from different disciplines.
    5. Find out new methods to improve his/her knowledge.
    6. Demonstrate sufficiency in English to follow literature, present technical projects and write articles
    7. Understand the social and global importance of proposed solutions

    Method of assessment

    1. Written exam
   Contents Up
Week 1: Introduction to cancer and general definitions
Week 2: Epidemiology: Global cancer burden
Week 3: From normal cell to malignant cell: Cellular factors
Week 4: Molecular mechanisms involved in transition from normal cell to malignant cell
Week 5: Introduction to environmental factors leading to transition from normal cell to malignant cell
Week 6: Environmental factors leading to transition from normal cell to malignant cell
Week 7: Introduction to metastasis
Mid-term exam
Week 8: Metastasis mechanisms
Week 9: Conventional therapeutics
Week 10: Personalized cancer treatment
Week 11: Novel diagnostic methods
Week 12: Big data for cancer research
Week 13: Bioengineering for cancer diagnosis and treatment & project presentations
Week 14: New developments in cancer biology
Week 15*: -
Week 16*: Final exam
Textbooks and materials: "Molecular Biology and Cancer: Mechanisms, Targets and Therapeutics" (2nd edition) - Lauren Pecorino, Oxford University Press

The Molecular Biology of Cancer- Micheal Khan, Stella Plengaris, Wiley-Blackwell
Recommended readings: “Hallmarks of cancer: the next generation.” Hanahan, Douglas, and Robert A Weinberg. Cell vol. 144,5 , 2011: 646-74. doi:10.1016/j.cell.2011.02.013
"Cancer Biology and Treatment (Oxford Biology Primers)" Divan, Royds, 2020, Oxford University Press
  * Between 15th and 16th weeks is there a free week for students to prepare for final exam.
Assessment Up
Method of assessment Week number Weight (%)
Mid-terms: 7 30
Other in-term studies: 0
Project: 13 30
Homework: 0
Quiz: 0
Final exam: 1 40
  Total weight:
(%)
   Workload Up
Activity Duration (Hours per week) Total number of weeks Total hours in term
Courses (Face-to-face teaching): 3 14
Own studies outside class: 2 14
Practice, Recitation: 0 0
Homework: 0 0
Term project: 2 13
Term project presentation: 1 1
Quiz: 0 0
Own study for mid-term exam: 2 7
Mid-term: 2 1
Personal studies for final exam: 2 5
Final exam: 2 1
    Total workload:
    Total ECTS credits:
*
  * ECTS credit is calculated by dividing total workload by 25.
(1 ECTS = 25 work hours)
-->