Syllabus ( BENG 461 )
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Basic information
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| Course title: |
Molecular Genetics |
| Course code: |
BENG 461 |
| Lecturer: |
Assoc. Prof. Dr. Bengü ERGÜDEN
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| ECTS credits: |
5 |
| GTU credits: |
3 () |
| Year, Semester: |
4, Fall and Spring |
| Level of course: |
First Cycle (Undergraduate) |
| Type of course: |
Area Elective
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| Language of instruction: |
English
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| Mode of delivery: |
Face to face
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| Pre- and co-requisites: |
BENG 223 |
| Professional practice: |
No |
| Purpose of the course: |
To introduce the structure, organization and maintenance of the genome; principles and control of the gene expression. |
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Learning outcomes
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Upon successful completion of this course, students will be able to:
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explain the structure and organization of the genome, DNA and RNA
Contribution to Program Outcomes
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Acquire knowledge on biological, chemical, physical and mathematical principles which constitute the basis of bioengineering applications
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Acquire knowledge on current bioengineering applications from the industrial and scientific aspects
Method of assessment
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Written exam
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define the basic mechanisms of gene expression
Contribution to Program Outcomes
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Acquire knowledge on biological, chemical, physical and mathematical principles which constitute the basis of bioengineering applications
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Acquire knowledge on current bioengineering applications from the industrial and scientific aspects
Method of assessment
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Written exam
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explain how molecular genetic mechanisms are controlled and describe the techniques used for this process.
Contribution to Program Outcomes
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Acquire knowledge on biological, chemical, physical and mathematical principles which constitute the basis of bioengineering applications
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Acquire knowledge on current bioengineering applications from the industrial and scientific aspects
Method of assessment
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Written exam
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Contents
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| Week 1: |
Nucleic acids, DNA and RNA |
| Week 2: |
The structure of genome |
| Week 3: |
Nucleosomes and chromatin |
| Week 4: |
Quiz I
DNA replication |
| Week 5: |
DNA mutations and repair mechanisms |
| Week 6: |
Quiz II
Mechanism of transcription |
| Week 7: |
Transcriptional Regulation and Posttranscriptional Modifications |
| Week 8: |
Midterm Exam
DNA-protein interactions |
| Week 9: |
Translation |
| Week 10: |
Translational control |
| Week 11: |
The genetic code |
| Week 12: |
Quiz III
Epigenetics |
| Week 13: |
Techniques of Molecular Biology |
| Week 14: |
Quiz IV
Model organisms |
| Week 15*: |
- |
| Week 16*: |
Final Exam |
| Textbooks and materials: |
Molecular Biology of the Gene. James D. Watson, Tania A. Baker, Stephen P. Bell, Alexander Gann, Michael Levine, Richard Losick. 7th ed. 2013. Pearson. |
| Recommended readings: |
1) Lewin’s Genes XII. Lewin, B. 9th ed. 2008. Jones and Bartlett Publishers.
2) Molecular Cell Biology. Harvey Lodish, Arnold Berk, Chris A. Kaiser, Monty Krieger, Matthew P. Scott, Anthony Bretscher, Hidde Ploegh, Paul Matsudaira. 8th Edition. Macmillan Learning.
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* Between 15th and 16th weeks is there a free week for students to prepare for final exam.
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Assessment
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| Method of assessment |
Week number |
Weight (%) |
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| Mid-terms: |
8 |
30 |
| Other in-term studies: |
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0 |
| Project: |
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0 |
| Homework: |
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0 |
| Quiz: |
5, 7, 12, 14 |
20 |
| Final exam: |
16 |
50 |
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Total weight: |
(%) |
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Workload
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| Activity |
Duration (Hours per week) |
Total number of weeks |
Total hours in term |
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| Courses (Face-to-face teaching): |
3 |
13 |
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| Own studies outside class: |
4 |
14 |
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| Practice, Recitation: |
0 |
0 |
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| Homework: |
0 |
0 |
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| Term project: |
0 |
0 |
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| Term project presentation: |
0 |
0 |
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| Quiz: |
1 |
4 |
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| Own study for mid-term exam: |
10 |
1 |
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| Mid-term: |
2 |
1 |
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| Personal studies for final exam: |
15 |
1 |
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| Final exam: |
2 |
1 |
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Total workload: |
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Total ECTS credits: |
* |
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* ECTS credit is calculated by dividing total workload by 25.
(1 ECTS = 25 work hours)
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