• Basic information
• Learning outcomes
• Contents
• Assessment
• Workload

Learning outcomes

Upon successful completion of this course, students will be able to:

1. To learn Biological warefare agents and mechanism of action

   Contribution to Program Outcomes

   1. Define, Chemical, Biological, Radiological and Nuclear (cbrn) concepts in a specialized way and apply them in CBRN defense
   2. Summarize, document, report and reflect on progress
   3. Develop stragies and/or product in order decicease risks of national and intenational CBRN threats
   4. Find out new methods to improve his/her knowledge
   5. Be aware of issues relating to the rights of other researchers and of research subjects e.g. confidentiality, attribution, copyright, ethics, malpractice, ownership of data

   Method of assessment

   1. Written exam
2. to learn about identify and determine of biological warefare agents

   Contribution to Program Outcomes

   1. Define, Chemical, Biological, Radiological and Nuclear (cbrn) concepts in a specialized way and apply them in CBRN defense
   2. Analyze critically and evaluate his/her findings and those of others
   3. Work effectively in multi-disciplinary research teams
   4. Effectively express his/her research ideas and findings both orally and in writing
   5. Apply of chemical, biological, radiological and nuclear concepts to individual, social, economic, technological and ethical aspects

   Method of assessment

   1. Written exam
3. Have knowledge about Biological Defense

   Contribution to Program Outcomes

   1. Understand relevant research methodologies and techniques and their appropriate application within his/her research field
   2. Develop stragies and/or product in order decicease risks of national and intenational CBRN threats
   3. Find out new methods to improve his/her knowledge
   4. Support his/her ideas with various arguments and present them clearly to a range of audience, formally and informally through a variety of techniques
   5. Apply of chemical, biological, radiological and nuclear concepts to individual, social, economic, technological and ethical aspects

   Method of assessment

   1. Written exam

Contents
Week 1:	Biological warfare agents: Introduction and History
Week 2:	Genetics of bacteria and viruses: Basic information
Week 3:	Biological warfare agents bacteria: Genetics and mechanism of action
Week 4:	Biological warfare agents bacteria: Genetics and mechanism of action
Week 5:	Biological warfare agents bacteria: Genetics and mechanism of action
Week 6:	Biological warfare agents viruses: Genetics and mechanism of action
Week 7:	Biological warfare agents viruses: Genetics and mechanism of action
Week 8:	Midterm exam
Week 9:	Biological warfare agents toxins and mechanism of action
Week 10:	Detection and identification systems against biological warfare agents
Week 11:	Identification systems based on nucleic acid technologies (NAT)
Week 12:	Identification systems based on nucleic acid technologies (NAT)
Week 13:	in vivo studies on biodefense and animal experiments
Week 14:	in vivo studies on biodefense and animal experiments
Week 15*:	characterization of unknown agents
Week 16*:	Final Exam
Textbooks and materials:	Ders notları, konuya ilişkin kitaplar ve makaleler
Recommended readings:	Wheelis M. Biological warfare before 1914. In: Moon JE van Courtland., editor. Biological and toxin weapons: Research, development, and use from the middle ages to 1945. Vol. 1. Stockholm, Sweden: Stockholm International Peace Research Institute; 1991. pp. 8–34. Christophe G, Cieslak T, Pavlin J, Eitzen E. Biological warfare: A historical perspective. JAMA. 1997;278:412–7. [PubMed]
	* Between 15th and 16th weeks is there a free week for students to prepare for final exam.

Assessment
Method of assessment	Week number	Weight (%)
Mid-terms:	8	35
Other in-term studies:		0
Project:		0
Homework:	10	15
Quiz:		0
Final exam:	16	50
	Total weight:	(%)

Workload
Activity	Duration (Hours per week)	Total number of weeks	Total hours in term
Courses (Face-to-face teaching):	3	14
Own studies outside class:	3	14
Practice, Recitation:	0	0
Homework:	6	10
Term project:	0	0
Term project presentation:	0	0
Quiz:	0	0
Own study for mid-term exam:	15	1
Mid-term:	1	1
Personal studies for final exam:	20	1
Final exam:	2	1
		Total workload:
		Total ECTS credits:	*
	* ECTS credit is calculated by dividing total workload by 25. (1 ECTS = 25 work hours)