• Basic information
• Learning outcomes
• Contents
• Assessment
• Workload

Learning outcomes

Upon successful completion of this course, students will be able to:

1. They can demonstrate an advanced understanding of selected topics in microbial physiology (cell structure, growth, biosynthesis, transport, etc.) through participation in class discussions, homework preparation, and oral presentations.

   Contribution to Program Outcomes

   1. Analyze critically and evaluate his/her findings and those of others
   2. Gain original, independent and critical thinking, and develop theoretical concepts and tools
   3. Find out new methods to improve his/her knowledge
   4. Effectively express his/her research ideas and findings both orally and in writing

   Method of assessment

   1. Homework assignment
   2. Seminar/presentation
2. Acquire the principles of energy-consuming and producing reactions in microorganism metabolism.

   Contribution to Program Outcomes

   1. Question and find out innovative approaches
   2. Gain original, independent and critical thinking, and develop theoretical concepts and tools
   3. Find out new methods to improve his/her knowledge
   4. Understand relevant health and safety issues and demonstrate responsible working practices

   Method of assessment

   1. Written exam
   2. Homework assignment
   3. Seminar/presentation
3. They embrace and explain various catabolic and anabolic pathways, transport systems and energy saving mechanisms in microorganisms.

   Contribution to Program Outcomes

   1. Define, Chemical, Biological, Radiological and Nuclear (cbrn) concepts in a specialized way and apply them in CBRN defense
   2. Question and find out innovative approaches
   3. Find out new methods to improve his/her knowledge
   4. Understand relevant health and safety issues and demonstrate responsible working practices

   Method of assessment

   1. Written exam
   2. Homework assignment

Contents
Week 1:	Overview of prokaryotic cell structure
Week 2:	Bacterial cytoplasmic membrane I: Phospholipid structure, energized membrane, respiratory chain proteins, influx, efflux
Week 3:	Bacterial cytoplasmic membrane II: Protein translocation, signal transduction, chemotaxis and motility
Week 4:	Bacterial cytoplasmic membrane III: DNA synthesis and cell division
Week 5:	Different mechanism of uptake substrates: Pasif diffusion, facilitated diffusion, active transport, group translocation
Week 6:	Midterm exam I
Week 7:	Fueling reactions I: Glycolysis, fermentative pathways
Week 8:	Fueling reactions II: Glycolysis, aerobic oxidation, and photosynthesis
Week 9:	Fueling reactions III: Anaerobic respirations, biosynthetic reactions
Week 10:	Regulation of metabolic pathways I: Regulation of enzyme activity, enzyme concentration
Week 11:	Midterm exam
Week 12:	Regulation of metabolic pathways II: Control of transcription initiation, control of translation
Week 13:	Regulation of metabolic pathways III: Regulation of whole level and metabolic pathway
Week 14:	Student presentations
Week 15*:	General evaluation
Week 16*:	Final Exam
Textbooks and materials:	Gerhard Gottschalk "Bacteria Metabolism" Springer Science & Business Media, Dec 6, 2012. Larry Barton "Structural and Functional Relationships in Prokaryotes" Springer Science & Business Media, 2005.
Recommended readings:	Wolfgang Eisenreich, Jürgen Heesemann, Thomas Rudel and Werner Goebel “Metabolic host responses to infection by intracellular bacterial pathogens” Front. Cell. Infect. Microbiol., 09 July. Joel H Weiner, Damaraju Sambasivarao, Richard A Rothery “Bacterial Cytoplasmic Membrane” Encyclopedıa of Life Sciences © 2001. Kazuyuki Shimizu” Metabolic Regulation of a Bacterial Cell System with Emphasis on Escherichia coli “, ISRN Biochemistry, Volume 2013,p.47
	* Between 15th and 16th weeks is there a free week for students to prepare for final exam.

Assessment
Method of assessment	Week number	Weight (%)
Mid-terms:	6,11	25
Other in-term studies:	0	0
Project:	14	25
Homework:	15	10
Quiz:	0	0
Final exam:	16	40
	Total weight:	(%)

Workload
Activity	Duration (Hours per week)	Total number of weeks	Total hours in term
Courses (Face-to-face teaching):	3	14
Own studies outside class:	3	14
Practice, Recitation:	0	0
Homework:	2	1
Term project:	1	1
Term project presentation:	1	1
Quiz:	0	0
Own study for mid-term exam:	10	3
Mid-term:	3	10
Personal studies for final exam:	10	4
Final exam:	2	1
		Total workload:
		Total ECTS credits:	*
	* ECTS credit is calculated by dividing total workload by 25. (1 ECTS = 25 work hours)