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Syllabus ( CBRN 534 )


   Basic information
Course title: Operational Prıncıples of Biosafety Level 3 Laboratory to Study Highly Patogenic Mikroorganisms
Course code: CBRN 534
Lecturer: Prof. Dr. Uygar Halis TAZEBAY
ECTS credits: 7,5
GTU credits: 3 (3+0+0)
Year, Semester: 2018-2019, Fall
Level of course: Second Cycle (Master's)
Type of course: Area Elective
Language of instruction: Turkish
Mode of delivery: Face to face
Pre- and co-requisites: none
Professional practice: No
Purpose of the course: Identification of biosafety and biosafety levels when working with high pathogenic microorganisms, establishment of biosafety rules in laboratory, biosafety applications and requirements, biosafety risk management, biosafety waste management, national and international regulations.
   Learning outcomes Up

Upon successful completion of this course, students will be able to:

  1. Learn the rules of working with different biosafety levels with high pathogenic microorganisms

    Contribution to Program Outcomes

    1. Define, Chemical, Biological, Radiological and Nuclear (cbrn) concepts in a specialized way and apply them in CBRN defense
    2. Understand relevant research methodologies and techniques and their appropriate application within his/her research field
    3. Analyze critically and evaluate his/her findings and those of others
    4. Summarize, document, report and reflect on progress
    5. Write progress reports clearly on the basis of published documents, thesis, etc
    6. Work effectively in multi-disciplinary research teams
    7. Asses risks of natura lor human made CBRN threats
    8. Find out new methods to improve his/her knowledge
    9. Support his/her ideas with various arguments and present them clearly to a range of audience, formally and informally through a variety of techniques
    10. Be aware of issues relating to the rights of other researchers and of research subjects e.g. confidentiality, attribution, copyright, ethics, malpractice, ownership of data

    Method of assessment

    1. Written exam
    2. Homework assignment
  2. BSL 3 Laboratuvarı Giriş - Çıkış Kuralları / Malzemelerin Taşınması/Atık bertaraf işlemleri kurallarını öğrenirler.

    Contribution to Program Outcomes

    1. Define, Chemical, Biological, Radiological and Nuclear (cbrn) concepts in a specialized way and apply them in CBRN defense
    2. Understand relevant research methodologies and techniques and their appropriate application within his/her research field
    3. Gain original, independent and critical thinking, and develop theoretical concepts and tools
    4. Work effectively in multi-disciplinary research teams
    5. Develop stragies and/or product in order decicease risks of national and intenational CBRN threats
    6. Develop an awareness of continuous learning in relation with modern technology
    7. Effectively express his/her research ideas and findings both orally and in writing
    8. Understand relevant health and safety issues and demonstrate responsible working practices
    9. Apply of chemical, biological, radiological and nuclear concepts to individual, social, economic, technological and ethical aspects

    Method of assessment

    1. Written exam
    2. Homework assignment
  3. Learn the rules of working with risk Manangment, Disinfection, Decontamination, Emergency plans in the BSL3 laboratory

    Contribution to Program Outcomes

    1. Define, Chemical, Biological, Radiological and Nuclear (cbrn) concepts in a specialized way and apply them in CBRN defense
    2. Understand relevant research methodologies and techniques and their appropriate application within his/her research field
    3. Analyze critically and evaluate his/her findings and those of others
    4. Gain original, independent and critical thinking, and develop theoretical concepts and tools
    5. Work effectively in multi-disciplinary research teams
    6. Develop an awareness of continuous learning in relation with modern technology
    7. Support his/her ideas with various arguments and present them clearly to a range of audience, formally and informally through a variety of techniques
    8. Be aware of issues relating to the rights of other researchers and of research subjects e.g. confidentiality, attribution, copyright, ethics, malpractice, ownership of data

    Method of assessment

    1. Written exam
    2. Homework assignment
   Contents Up
Week 1: Introduction to Biosafety

Week 2: BSL3 Education - Health and Medical Surveillance
Week 3: Biosafety Level 1-2-3-4 (BSL 1-2-3-4) Laboratory Specifications and Usage

Week 4: Biosafety Level 3 Laboratory Equipment and Materials
Week 5: Biosafety Level 3 Laboratory Laboratory Input - Output Rules and Use of Personal Protective Equipment
Week 6: Biosafety Level 3 Laboratory Disinfection, Decontamination
Week 7: Waste Transport and Disposal Operations / Animal Biosafety Level 3 (ABSL 3) Laboratory studies

Week 8: Mid-term
Week 9: Biosafety Level 3 Laboratory Emergency plans
Week 10: Biosafety Level 3 Laboratory Risk Assessment Studies
Week 11: Microbiological Monitoring / Validation in Biosafety Level 3 Laboratory
Week 12: Biosafety Level 3 Laboratory Infrastructure performance tests
Week 13: Required Charts for Laboratory Sustainability
Week 14: BSL3 Application studies in Biosafety Level 3 Laboratory
Week 15*: Term Paper and BSL3 Application studies in Biosafety Level 3 Laboratory
Week 16*: Final Exam
Textbooks and materials: WHO Laboratory biosafety manual,Third edition, 2004,
Biosafety in Microbiological and Biomedical Laboratories,U.S. Department
of Health and Human Services Public Health Service Centers for Disease Control and Prevention and National Institutes of Health, 5th Edition 2009,
The Laboratory Biosafety Guidelines 3th Edition, Minister of Health Population and Public Health Branch Centre for Emergency Preparedness and Response, 2004,
Veterinary Containment Facilities, Design & Construction, Handbook, International Veterinary Biosafety Working Group,2006,
Recommended readings: TS and EU standards on clean room technology
  * Between 15th and 16th weeks is there a free week for students to prepare for final exam.
Assessment Up
Method of assessment Week number Weight (%)
Mid-terms: 8 40
Other in-term studies: 0
Project: 0
Homework: 15 10
Quiz: 0
Final exam: 16 50
  Total weight:
(%)
   Workload Up
Activity Duration (Hours per week) Total number of weeks Total hours in term
Courses (Face-to-face teaching): 3 14
Own studies outside class: 6 14
Practice, Recitation: 0 0
Homework: 0 0
Term project: 15 1
Term project presentation: 1 1
Quiz: 1 1
Own study for mid-term exam: 20 1
Mid-term: 2 1
Personal studies for final exam: 20 1
Final exam: 2 1
    Total workload:
    Total ECTS credits:
*
  * ECTS credit is calculated by dividing total workload by 25.
(1 ECTS = 25 work hours)
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