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Syllabus ( CBRN 537 )


   Basic information
Course title: Chemical Warfare Agents, Toxic Industrial Chemicals and Their Detection Methods
Course code: CBRN 537
Lecturer: Prof. Dr. Uygar Halis TAZEBAY
ECTS credits: 7.5
GTU credits: 3 (3+0+0)
Year, Semester: 2018-2019, Spring
Level of course: Second Cycle (Master's)
Type of course: Area Elective
Language of instruction: Turkish
Mode of delivery: Face to face
Pre- and co-requisites: none
Professional practice: No
Purpose of the course: The purpose is to provide the students with the basic knowledge on CWAs and TICs, the necessary theoretical background and fundamental concepts of the various detection methods and an overview on the state of the art instrumentation for laboratory and field use. Besides, the course will provide the fundamental knowledge to understand and interpret the results of the most common analysis methods and provide the necessary background to assess and evaluate scientific and technical literature in the field.
   Learning outcomes Up

Upon successful completion of this course, students will be able to:

  1. Name and classify the most common CWAs and TICs, understand their hazards for the human health, and to devise detection possibilities based on their chemical and physical properties

    Contribution to Program Outcomes

    1. Define, Chemical, Biological, Radiological and Nuclear (cbrn) concepts in a specialized way and apply them in CBRN defense
    2. Summarize, document, report and reflect on progress
    3. Work effectively in multi-disciplinary research teams
    4. Find out new methods to improve his/her knowledge
    5. Support his/her ideas with various arguments and present them clearly to a range of audience, formally and informally through a variety of techniques
    6. Understand relevant health and safety issues and demonstrate responsible working practices

    Method of assessment

    1. Written exam
  2. Part of the homework and the exams will test the student’s understanding of the provided background by solving simple and advanced questions on textbook level.

    Contribution to Program Outcomes

    1. Define, Chemical, Biological, Radiological and Nuclear (cbrn) concepts in a specialized way and apply them in CBRN defense
    2. Analyze critically and evaluate his/her findings and those of others
    3. Asses risks of natura lor human made CBRN threats
    4. Develop an awareness of continuous learning in relation with modern technology
    5. Effectively express his/her research ideas and findings both orally and in writing
    6. Apply of chemical, biological, radiological and nuclear concepts to individual, social, economic, technological and ethical aspects

    Method of assessment

    1. Written exam
    2. Oral exam
  3. Understand, critical assess and evaluate scientific and technical papers on CWA and TIC detection

    Contribution to Program Outcomes

    1. Define, Chemical, Biological, Radiological and Nuclear (cbrn) concepts in a specialized way and apply them in CBRN defense
    2. Question and find out innovative approaches
    3. Asses risks of natura lor human made CBRN threats
    4. Develop an awareness of continuous learning in relation with modern technology
    5. Support his/her ideas with various arguments and present them clearly to a range of audience, formally and informally through a variety of techniques

    Method of assessment

    1. Written exam
   Contents Up
Week 1: Introduction, basic concepts and terminology
Week 2: Chemical Warfare Agents (CWAs)

Week 3: Toxic Industrial Chemicals (TICs)
Week 4: CWAs, TICs, simulants and their detection
Week 5: Overview on detection technologies: fundamental concepts and theoretical background
Week 6: Gas sampling techniques, gas chromatography
Week 7: Midterm exam
Week 8: Mass spectrometry and ion mobility spectrometry
Week 9: Spectroscopic methods
Week 10: Chemical sensors
Week 11: Chemical sensor systems
Week 12: Biosensors and other detection technologies
Week 13: Sampling and detection in the liquid phase
Week 14: Current detection systems and devices for laboratory and field use
Week 15*: A review of current trends and new detection technologies

Week 16*: Final Exam
Textbooks and materials: 3-4 current scientific articles to be announced, lecture slides
Recommended readings: K. Ganesan, S. K. Raza , R. Vijayaraghavan. Chemical warfare agents. Journal of Pharmacy and Bioallied Sciences, 2 (2010) 166–178, DOI: 10.4103/0975-7406.68498
S. Chauhan, S. Chauhan, R. D’Cruz, S. Faruqi, K.K. Singh, S. Varma, M. Singh, V. Karthik. Chemical warfare agents, In Environmental Toxicology and Pharmacology, 26 (2008) 113-122, DOI: 10.1016/j.etap.2008.03.003.
K. Kim, O. G. Tsay, D. A. Atwood, D. G. Churchill. Destruction and Detection of Chemical Warfare Agents, Chemical Reviews, 111 (2011) 5345-5403, DOI: 10.1021/cr100193y (Sections “Introduction” and “Detection”)
E. J. Pacsial-Ong, Z. P. Aguilar. Chemical warfare agent detection: a review of current trends and future perspective, Frontiers in Bioscience S5 (2013) 516-543, DOI10.2741/S387

General textbooks on analytical chemistry.

Web resources for further readings:
Centers for Disease Control and Prevention. Chemical Agents, https://emergency.cdc.gov/Agent/AgentlistChem.asp
Organisation for the Prohibition of Chemical Weapons, Articles of the Chemical Weapons Convention, https://www.opcw.org/chemical-weapons-convention/articles/
Organisation for the Prohibition of Chemical Weapons, Protection Against Chemical Weapons, https://www.opcw.org/protection/
  * Between 15th and 16th weeks is there a free week for students to prepare for final exam.
Assessment Up
Method of assessment Week number Weight (%)
Mid-terms: 7 30
Other in-term studies: 0
Project: 0
Homework: 10 20
Quiz: 0
Final exam: 16 50
  Total weight:
(%)
   Workload Up
Activity Duration (Hours per week) Total number of weeks Total hours in term
Courses (Face-to-face teaching): 3 14
Own studies outside class: 3 14
Practice, Recitation: 0 0
Homework: 6 10
Term project: 0 0
Term project presentation: 0 0
Quiz: 0 0
Own study for mid-term exam: 15 1
Mid-term: 1 1
Personal studies for final exam: 20 1
Final exam: 2 1
    Total workload:
    Total ECTS credits:
*
  * ECTS credit is calculated by dividing total workload by 25.
(1 ECTS = 25 work hours)
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