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Syllabus ( CED 542 )


   Basic information
Course title: Microchemical and Microfluidic Systems
Course code: CED 542
Lecturer: Assist. Prof. Muhammed Enes ORUÇ
ECTS credits: 7.5
GTU credits: 3 (3+0+0)
Year, Semester: 2018-2019, Fall and Spring
Level of course: Second Cycle (Master's)
Type of course: Area Elective
Language of instruction: English
Mode of delivery: Face to face
Pre- and co-requisites: none
Professional practice: No
Purpose of the course: This course aims to provide an understanding of the many necessary skills for conceiving and designing bioMEMS (Micro-Electro-Mechanical Systems) and medical microdevices, and for applying them to research and medicine. This includes fabrication with silicon, glass, and polymers substrates; covalent and noncovalent surface modifications; self-assembled monolayers (SAMs); transport processes such as laminar flow and electrokinetic phenomena; sorting, isolation, separation of biomolecules; and single-molecule detection.
   Learning outcomes Up

Upon successful completion of this course, students will be able to:

  1. It will provide the knowledge about the BioMEMS fabrication.

    Contribution to Program Outcomes

    1. Define and manipulate advanced concepts of Chemical Engineering
    2. Review the literature critically pertaining to his/her research projects, and connect the earlier literature to his/her own results,
    3. Work effectively in multi-disciplinary research teams
    4. Develop an awareness of continuous learning in relation with modern technology
    5. Effectively express his/her research ideas and findings both orally and in writing

    Method of assessment

    1. Written exam
    2. Term paper
  2. It will identify miniaturization issues on life sciences.

    Contribution to Program Outcomes

    1. Define and manipulate advanced concepts of Chemical Engineering
    2. Review the literature critically pertaining to his/her research projects, and connect the earlier literature to his/her own results,
    3. Acquire scientific knowledge
    4. Develop an awareness of continuous learning in relation with modern technology
    5. Effectively express his/her research ideas and findings both orally and in writing

    Method of assessment

    1. Written exam
    2. Term paper
  3. Students will learn microfluidic platforms.

    Contribution to Program Outcomes

    1. Review the literature critically pertaining to his/her research projects, and connect the earlier literature to his/her own results,
    2. Work effectively in multi-disciplinary research teams
    3. Develop an awareness of continuous learning in relation with modern technology
    4. Effectively express his/her research ideas and findings both orally and in writing

    Method of assessment

    1. Written exam
    2. Term paper
  4. Students will demonstrate creative solutions at the interface of biology and technology.

    Contribution to Program Outcomes

    1. Define and manipulate advanced concepts of Chemical Engineering
    2. Review the literature critically pertaining to his/her research projects, and connect the earlier literature to his/her own results,
    3. Work effectively in multi-disciplinary research teams
    4. Develop an awareness of continuous learning in relation with modern technology
    5. Effectively express his/her research ideas and findings both orally and in writing

    Method of assessment

    1. Written exam
    2. Term paper
   Contents Up
Week 1: Introduction to BioMEMS
Week 2: Scaling laws
Week 3: Microfabrication process- Additive Methods
Week 4: Microfabrication process- Subtractive Methods
Week 5: Polymer-based microfabrication
Week 6: Fluidics basics
Week 7: Microfluidic control & measurement
Week 8: MIDTERM
Week 9: Forces and fields at the microscale
Week 10: Lab-on-chip systems
Week 11: Sorting, isolation, separation of biomolecules
Week 12: Single-Molecule detection
Week 13: Micro/Nano biosensors
Week 14: Drug Delivery / Implantation Devices
Week 15*: -
Week 16*: FINAL
Textbooks and materials: * Introduction to BioMEMS, Albert Folch, CRC Press, 2012.
* Ders notları
Recommended readings: * Fundamentals of Microfabrication, Marc J. Madou, CRC Press, 2011
* Biomedical Microsystems, Ellis Meng, CRC Press, 2010.
  * Between 15th and 16th weeks is there a free week for students to prepare for final exam.
Assessment Up
Method of assessment Week number Weight (%)
Mid-terms: 8 30
Other in-term studies: 0
Project: 9,11,13 30
Homework: 0
Quiz: 0
Final exam: 16 40
  Total weight:
(%)
   Workload Up
Activity Duration (Hours per week) Total number of weeks Total hours in term
Courses (Face-to-face teaching): 3 14
Own studies outside class: 4 14
Practice, Recitation: 0 0
Homework: 0 0
Term project: 12 5
Term project presentation: 0 0
Quiz: 0 0
Own study for mid-term exam: 10 1
Mid-term: 3 1
Personal studies for final exam: 10 1
Final exam: 3 1
    Total workload:
    Total ECTS credits:
*
  * ECTS credit is calculated by dividing total workload by 25.
(1 ECTS = 25 work hours)
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