Syllabus ( MBG 445 )
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Basic information
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| Course title: |
Introduction to Synthetic Biology |
| Course code: |
MBG 445 |
| Lecturer: |
Assoc. Prof. Dr. Özlem AKKAYA
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| ECTS credits: |
5 |
| GTU credits: |
3 (3-0-0) |
| Year, Semester: |
2022-2023, Fall |
| Level of course: |
First Cycle (Undergraduate) |
| Type of course: |
Elective
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| Language of instruction: |
English
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| Mode of delivery: |
Face to face , Group study
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| Pre- and co-requisites: |
none |
| Professional practice: |
No |
| Purpose of the course: |
The overall goal of the course is to introduce to students with the important methods, strategies and applications of synthetic biology which is one of the most promising new technologies. |
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Learning outcomes
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Upon successful completion of this course, students will be able to:
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Define synthetic biology and understand its importance in this century
Contribution to Program Outcomes
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To be able to define general concepts and problems related to Molecular Biology and Genetics and to produce solutions.
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To be able to comprehend the history and nature of scientific thinking and to apply them to problems in the field.
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To be able to work individually, make independent decisions and participate actively in multidisciplinary group studies.
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To be able to follow current scientific and technological innovations with the awareness of continuous learning and to apply them in the field.
Method of assessment
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Written exam
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Homework assignment
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Understand fundamental concepts, principles and methods of synthetic biology
Contribution to Program Outcomes
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To be able to define general concepts and problems related to Molecular Biology and Genetics and to produce solutions.
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To be able to follow current scientific and technological innovations with the awareness of continuous learning and to apply them in the field.
Method of assessment
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Written exam
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Introduce key questions of ethics and biosafety on the responsible use of this new technology
Contribution to Program Outcomes
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To be able to work individually, make independent decisions and participate actively in multidisciplinary group studies.
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To be able to embrace academic ethical rules and to be able to act with a sense of responsibility.
Method of assessment
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Written exam
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Homework assignment
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Contents
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| Week 1: |
What is Synthetic Biology? |
| Week 2: |
The emergence of synthetic biology |
| Week 3: |
Fundamentals of DNA Engineering
-BioBricks and Standard Biological Parts
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| Week 4: |
Fundamentals of biodesing from biological parts to genetic circuits |
| Week 5: |
Synthetic biology and bioengineering |
| Week 6: |
Synthetic biology and genom editing |
| Week 7: |
Midterm exam |
| Week 8: |
Synthetic biology and chassis engineering |
| Week 9: |
Synthetic biology and metabolic engineering |
| Week 10: |
Social and ethical perspectives in synthetic biology |
| Week 11: |
Applications of synthetic biology |
| Week 12: |
iGEM Projects-1 |
| Week 13: |
iGEM Projects-2 |
| Week 14: |
iGEM Projects-3 |
| Week 15*: |
General overview |
| Week 16*: |
Final exam |
| Textbooks and materials: |
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| Recommended readings: |
Porcar, M., & Peretó, J. (2014). Synthetic biology: from iGEM to the artificial cell. Springer Netherlands.
Kuldell, N., Bernstein, R., Ingram, K., & Hart, K. M. (2015). BioBuilder: Synthetic biology in the lab. O'Reilly.
Baldwin, G. (2012). Synthetic biology: A primer. John Wiley & Sons.
Church, G. M., & Regis, E. (2014). Regenesis: how synthetic biology will reinvent nature and ourselves. Basic Books.
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* Between 15th and 16th weeks is there a free week for students to prepare for final exam.
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Assessment
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| Method of assessment |
Week number |
Weight (%) |
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| Mid-terms: |
7 |
25 |
| Other in-term studies: |
0 |
0 |
| Project: |
0 |
0 |
| Homework: |
15 |
25 |
| Quiz: |
0 |
0 |
| Final exam: |
16 |
50 |
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Total weight: |
(%) |
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Workload
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| Activity |
Duration (Hours per week) |
Total number of weeks |
Total hours in term |
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| Courses (Face-to-face teaching): |
3 |
14 |
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| Own studies outside class: |
3 |
14 |
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| Practice, Recitation: |
0 |
0 |
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| Homework: |
20 |
1 |
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| Term project: |
0 |
0 |
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| Term project presentation: |
0 |
0 |
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| Quiz: |
0 |
0 |
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| Own study for mid-term exam: |
8 |
1 |
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| Mid-term: |
3 |
1 |
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| Personal studies for final exam: |
10 |
1 |
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| Final exam: |
3 |
1 |
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Total workload: |
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Total ECTS credits: |
* |
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* ECTS credit is calculated by dividing total workload by 25.
(1 ECTS = 25 work hours)
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