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Syllabus ( MBG 544 )


   Basic information
Course title: Biomaterials and Applications
Course code: MBG 544
Lecturer: Assist. Prof. Ayşe ASLAN CANPOLAT
ECTS credits: 7.5
GTU credits: 3 (3+0+0)
Year, Semester: 2, Spring
Level of course: Second Cycle (Master's)
Type of course: Area Elective
Language of instruction: Turkish
Mode of delivery: Face to face
Pre- and co-requisites: None
Professional practice: No
Purpose of the course: The course will focus mainly on the field of biomaterials used in the design of medical devices, and to augment or replace soft and hard tissues. Discussion of bulk properties, applications, and in vivo behavior of different classes of natural and synthetic biomaterials. Analysis of biological response and biocompatibility, degradation and failure processes of implantable biomaterials/devices.
   Learning outcomes Up

Upon successful completion of this course, students will be able to:

  1. Key areas of achievements will be obtaining necessary information about the basic principles of biomaterials and applying this know-how for the solution of problems

    Contribution to Program Outcomes

    1. Define and manipulate advanced concepts of Biology
    2. Define the relationship among life forms and their environments and ecosystems
    3. Acquire scientific knowledge and work independently,
    4. Work effectively in multi-disciplinary research teams
    5. Find out new methods to improve his/her knowledge.
    6. Effectively express his/her research ideas and findings both orally and in writing
    7. Demonstrate professional and ethical responsibility.
    8. Apply biological concepts to personal, social, economical, technological and ethical issues

    Method of assessment

    1. Written exam
    2. Seminar/presentation
  2. Know the basic features of selection and use of biomaterials

    Contribution to Program Outcomes

    1. Define and manipulate advanced concepts of Biology
    2. Critically review the literature pertaining to his/her research projects, and connect the earlier literature to his/her own results,
    3. Define the relationship among life forms and their environments and ecosystems
    4. Develop an understanding of matter and energy in organisms
    5. Acquire scientific knowledge and work independently,
    6. Work effectively in multi-disciplinary research teams
    7. Find out new methods to improve his/her knowledge.
    8. Effectively express his/her research ideas and findings both orally and in writing
    9. Apply biological concepts to personal, social, economical, technological and ethical issues

    Method of assessment

    1. Written exam
    2. Seminar/presentation
  3. Understand the roles of biomaterials in the production of artificial organs and biosensors.

    Contribution to Program Outcomes

    1. Define and manipulate advanced concepts of Biology
    2. Critically review the literature pertaining to his/her research projects, and connect the earlier literature to his/her own results,
    3. Define the relationship among life forms and their environments and ecosystems
    4. Develop an understanding of matter and energy in organisms
    5. Identify structure-function relationships in cells and organisms
    6. Ability to work independently and take responsibility
    7. Acquire scientific knowledge and work independently,
    8. Work effectively in multi-disciplinary research teams
    9. Find out new methods to improve his/her knowledge.
    10. Understand the applications and basic principles of new instrumentation and/or software vital to his/her thesis projects.
    11. Effectively express his/her research ideas and findings both orally and in writing
    12. Demonstrate professional and ethical responsibility.
    13. Apply biological concepts to personal, social, economical, technological and ethical issues

    Method of assessment

    1. Written exam
    2. Seminar/presentation
   Contents Up
Week 1: Introduction to Biomaterials; An Evolving, Multidisciplinary Endeavour

Week 2: Classes of Materials used in Medicine (metals): Synthesis and characterization of metals for biomedical applications
Week 3: Classes of Materials used in Medicine (polymers); Synthesis and characterization of polymers for biomedical applications

Week 4: Classes of Materials used in Medicine (seramics); Synthesis and characterization of seramics for biomedical applications

Week 5: Classes of Materials used in Medicine (composites); Synthesis and characterization of composites for biomedical applications

Week 6: Biological Recognition; Materials - applications relationships of biomaterials, Biocompatibility
Week 7: Host Reaction to Biomaterials and their Evaluation; tissue response to implants, side effects reactions,
Week 8: Midterm exam
Week 9: Biological Testing of Biomaterials:, Mechanical properties of biomaterial,
Week 10: Degradation of Materials in the Biological Environment : chemical stability of biomaterials, degradation mechanism of materials
Week 11: Application of Biomaterials; Application areas of composite,metal and ceramic materials
Week 12: Application of Biomaterials; Application areas of polymeric materials
Week 13: Student presentations; discussions of novel applications and biomaterials

Week 14: Student presentations;discussions of novel applications and biomaterials
Week 15*: Review of course materials: Evaluation of course
Week 16*: Final exam
Textbooks and materials: İlgili derleme makaleler ve kitap bölümleri (Öğretim Üyesi tarafından elektronik kopyalar halinde öğrencilere iletilecek
Recommended readings: Biomaterials Science: An Introduction to Materials in Medicine”, B.D. Ratner, A.S. Hoffman, F.J. Schoen, J.E. Lemans, Academic Press, 1996
"Introduction to Biomaterials" Donglu Shi, Tsinghua University Press
  * Between 15th and 16th weeks is there a free week for students to prepare for final exam.
Assessment Up
Method of assessment Week number Weight (%)
Mid-terms: 8 25
Other in-term studies: 0
Project: 13-14 25
Homework: 0
Quiz: 0
Final exam: 16 50
  Total weight:
(%)
   Workload Up
Activity Duration (Hours per week) Total number of weeks Total hours in term
Courses (Face-to-face teaching): 3 14
Own studies outside class: 5 14
Practice, Recitation: 0 0
Homework: 0 0
Term project: 3 2
Term project presentation: 3 2
Quiz: 0 0
Own study for mid-term exam: 2 4
Mid-term: 2 3
Personal studies for final exam: 10 4
Final exam: 3 3
    Total workload:
    Total ECTS credits:
*
  * ECTS credit is calculated by dividing total workload by 25.
(1 ECTS = 25 work hours)
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