Syllabus ( MBG 640 )
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Basic information
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Course title: |
Advanced Neurobiology |
Course code: |
MBG 640 |
Lecturer: |
Prof. Dr. Işıl KURNAZ
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ECTS credits: |
7.5 |
GTU credits: |
3 (3+0+0) |
Year, Semester: |
2024, Fall and Spring |
Level of course: |
Third Cycle (Doctoral) |
Type of course: |
Area Elective
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Language of instruction: |
English
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Mode of delivery: |
Face to face
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Pre- and co-requisites: |
none |
Professional practice: |
No |
Purpose of the course: |
Information about nervous system development, embryonic and adult neurogenesis concepts and importance of neurogenesis on learning, memory and neurodegenerative disorders; discussion of neurorestorative therapies; to enable the students to follow up-to-date techniques and publications
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Learning outcomes
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Upon successful completion of this course, students will be able to:
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They can define embryonic and adult neurogenesis
Contribution to Program Outcomes
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Define and manipulate advanced concepts of Biology in a specialized way
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Effectively express his/her research ideas and findings both orally and in writing
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Apply biological concepts to personal, social, economical, technological and ethical issues
Method of assessment
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Written exam
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Homework assignment
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Term paper
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They can follow contemporary publications on neurodegenerative disorders and neurogenesis and learn about recent technologies.
Contribution to Program Outcomes
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Define and manipulate advanced concepts of Biology in a specialized way
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Question and find out innovative approaches.
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Gain original, independent and critical thinking, and develop theoretical concepts and tools,
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Develop an awareness of continuous learning in relation with modern technology
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Effectively express his/her research ideas and findings both orally and in writing
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Apply biological concepts to personal, social, economical, technological and ethical issues
Method of assessment
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Written exam
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Homework assignment
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Term paper
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They comprehend the correlation between learning -memory and neurogenesis.
Contribution to Program Outcomes
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Define and manipulate advanced concepts of Biology in a specialized way
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Develop an awareness of continuous learning in relation with modern technology
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Effectively express his/her research ideas and findings both orally and in writing
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Support his/her ideas with various arguments and present them clearly to a range of audience, formally and informally through a variety of techniques
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Apply biological concepts to personal, social, economical, technological and ethical issues
Method of assessment
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Written exam
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Homework assignment
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Term paper
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Contents
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Week 1: |
Introduction to the Neuron at the Cellular and Molecular Level |
Week 2: |
Development of the nervous system – embryonic neurogenesis |
Week 3: |
Development of the nervous system – axon growth and guidance |
Week 4: |
Molecular mechanisms of synaptic plasticity |
Week 5: |
Molecular mechanisms and gene expression in LTP and LTD |
Week 6: |
Adult neurogenic zones and adult neurogenesis |
Week 7: |
Adult neurogenesis in learning and memory |
Week 8: |
neural stem cell isolation and manipulation |
Week 9: |
Neurodegenerative disorders - Alzheimer's genetics and pathology |
Week 10: |
Neurodegenerative disorders - Parkinson's genetics and pathology |
Week 11: |
Neurodegenerative disorders - Huntington's genetics and pathology |
Week 12: |
Neurodegenerative disorders - ALS genetics and pathology |
Week 13: |
Brain and spinal cord traumas |
Week 14: |
Neural stem cell and tissue engineering approaches to traumatic brain injury |
Week 15*: |
Term project presentations |
Week 16*: |
Term project presentations |
Textbooks and materials: |
• Principles of Neuroscience; Kandel, Schwartz and Jessell, McGraw Hill, 2000 (ISBN-10: 9780838577011; ISBN-13: 978-0838577011) • Contemporary articles (as pdf files) |
Recommended readings: |
• Principles of Neuroscience; Kandel, Schwartz and Jessell, McGraw Hill, 2000 (ISBN-10: 9780838577011; ISBN-13: 978-0838577011) • Contemporary articles (as pdf files) |
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* Between 15th and 16th weeks is there a free week for students to prepare for final exam.
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Assessment
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Method of assessment |
Week number |
Weight (%) |
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Mid-terms: |
5 |
15 |
Other in-term studies: |
9,10,11,12,13,14 |
60 |
Project: |
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0 |
Homework: |
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0 |
Quiz: |
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0 |
Final exam: |
15 |
25 |
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Total weight: |
(%) |
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Workload
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Activity |
Duration (Hours per week) |
Total number of weeks |
Total hours in term |
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Courses (Face-to-face teaching): |
3 |
16 |
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Own studies outside class: |
3 |
16 |
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Practice, Recitation: |
0 |
0 |
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Homework: |
6 |
6 |
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Term project: |
20 |
1 |
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Term project presentation: |
6 |
1 |
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Quiz: |
0 |
0 |
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Own study for mid-term exam: |
6 |
1 |
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Mid-term: |
1 |
1 |
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Personal studies for final exam: |
20 |
1 |
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Final exam: |
1 |
1 |
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Total workload: |
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Total ECTS credits: |
* |
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* ECTS credit is calculated by dividing total workload by 25. (1 ECTS = 25 work hours)
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